The threat of bio terrorism or CBRN is now a major threat with the security services Mi5 now Mi5 the UK security agency warning that the current threat level of attack is "Severe" just one level down from the highest risk assessment "Critical". Tony Blair has stated, "The security threat we face is not conventional. It is a challenge of a different nature from anything the world has faced before". CBRN Chemical Biological Radiological Nuclear and Bio terrorism are typically the threats and hazards recognised and their specific threats and hazards and effects must be removed or reduced. CBRN and Bio terrorism are the new forms of terrorist weaponry and they are readily available in the commercial world. Planning to defend buildings and protect occupants against both CBRN and bio terrorism should be a vital component of any Business continuity plan.